hrp0084p2-275 | Diabetes | ESPE2015

Do Pancreatic Functions Predict Cardiac and Liver Iron Loading in Transfusion-Dependent β-Thalassemia Major Patients Using Cardiovascular and Liver T2-Star (T2*)Magnetic Resonance?

Mokhtar Galila , Ibrahim Wafaa , Elbarbary Nancy , Matter Randa , Ibrahim Ahmed , Sayed Safa

Background: Regular and frequent red blood cell transfusions have significantly increased the life expectancy of patients with β-thalassemia major (β-TM). However, when no appropriate chelation therapy is available, patients accumulate iron in the heart, liver, spleen, pancreas, and endocrine glands, leading to progressive organ dysfunction.Objective and hypotheses: To assess the correlation between cardiac and hepatic T2*MRI findings with the ...